Hyponatremia with carcinoma of the bronchus.

SEVERAL previous reports have described the occurrence of hyponatrmmia with carcinoma of the bronchus, and inappropriate secretion of antidiuretic hormone was suggested as the mechanism accounting for the low serum sodium. (Schwartz, Bennett, Curelop and Bartter 1957, Roberts 1959, Turner and Williams, 1962.) Rees, Rosalki and Maclean (I960), described a case of carcinoma of the bronchus in which theyv. considered renal tubular damage accounted for the low serum sodium, in the absence of evidence of excessive secretion of antidiuteric hormone. We wish to report a further case of carcinoma of bronchus with hyponatroemia, in which there was evidence of renal tubular damage. In addition, there was evidence of adrenal hyperactivity.